Prevalence and Pattern of Self-Medication for Melasma among University Students: A Cross-Sectional Survey

Authors

  • Shakeel Ijaz Quaid-e-Azam College of Pharmacy, Sahiwal, Pakistan. Central Park College of Pharmacy, Lahore, Pakistan
  • Sana Yousaf Quaid-e-Azam College of Pharmacy, Sahiwal, Pakistan
  • Aousaf Ahmad Quaid-e-Azam College of Pharmacy, Sahiwal, Pakistan
  • Farheen Zia Quaid-e-Azam College of Pharmacy, Sahiwal, Pakistan
  • Insha Akram Quaid-e-Azam College of Pharmacy, Sahiwal, Pakistan
  • Aimen Arshad Quaid-e-Azam College of Pharmacy, Sahiwal, Pakistan
  • Iqra Afzal Quaid-e-Azam College of Pharmacy, Sahiwal, Pakistan
  • Asma Iftikhar Quaid-e-Azam College of Pharmacy, Sahiwal, Pakistan
  • Shanza Zafar Quaid-e-Azam College of Pharmacy, Sahiwal, Pakistan
  • Usama Rehman Quaid-e-Azam College of Pharmacy, Sahiwal, Pakistan
  • Nisha Khalid Quaid-e-Azam College of Pharmacy, Sahiwal, Pakistan

DOI:

https://doi.org/10.65761/pjcr.2026.317

Keywords:

Melasma; Self-medication; University students; Skin-lightening products; Community pharmacy

Abstract

Background: Melasma is common in young women with darker skin, and the crowded market of whitening creams, steroids and herbal products makes it a natural target for self-medication. How students manage the condition, and how safely, is poorly documented in Pakistan. We measured the prevalence and patterns of self-medication for melasma, and the attitudes surrounding it, among university students.

Methods: In a cross-sectional survey across South Punjab (July-August 2025), 438 students completed a self-administered questionnaire covering demographics, melasma awareness and experience, treatment-seeking, products used, side effects, and attitudes. We analysed responses in SPSS using descriptive statistics.

Results: Most respondents were women (64.2%), aged 18-23 (85.6%), and enrolled in health-sciences faculties (89.0%). Awareness of melasma was high (82.6%), most often acquired from the internet or social media (34.0%), yet only 24.7% had ever been formally diagnosed. Among those who acted, fewer than half sought help (45.0%); dermatologists were the most common first contact (59.6%), but pharmacies supplied most self-medication (54.8%), and about 30% used prescription-type products without a prescription. Reported agents included vitamins (25.5%), hydroquinone (14.1%), organic acids (12.9%) and retinoids (9.2%); roughly half tried home remedies. Self-medication caused side effects in 22.7%. Despite this, 74.8% considered dermatologist consultation necessary and 71.9% backed awareness campaigns.

Conclusion: Awareness of melasma was high but rarely translated into supervised care. Self-management was pharmacy-driven and frequently unsupervised, with a meaningful side-effect burden. This gap between knowledge and safe practice is one community pharmacists are well placed to close.

References

1. Ogbechie-Godec OA, Elbuluk N. Melasma: an up-to-date comprehensive review. Dermatol Ther (Heidelb). 2017;7(3):305-318. doi:10.1007/s13555-017-0194-1.

2. Jiang J, Akinseye O, Tovar-Garza A, Pandya AG. The effect of melasma on self-esteem: a pilot study. Int J Womens Dermatol. 2018;4(1):38-42. doi:10.1016/j.ijwd.2017.11.003.

3. Yang W, Meng X, Liu T, Chen N, Li D, Xu Y. The exposome in melasma: a comprehensive review of etiology, mechanisms, and implications for management. Clin Cosmet Investig Dermatol. 2026;19:594944. doi:10.2147/CCID.S594944.

4. Oh SM, Lee YE, Ko MJ, Baek JH, Shin MK. Proposal of facial pigmentary unit and facial hyperpigmentation type for Fitzpatrick skin types II-IV. Skin Res Technol. 2023;29(1). doi:10.1111/srt.13251.

5. Kalegore S, Pathan A, Nilangekar S, Mujawar A, Sirgire K. Global epidemiology: melasma. Int J Pharm Sci. 2026;4(1):1521-1533. doi:10.5281/zenodo.18257366.

6. Malkani RH, Narula S, Lulla C, Karmakar S, Choubisa J, Sharma A, et al. A study of factors associated with melasma and quality of life in patients with melasma: a case-control study. Cureus. 2026;18(2). doi:10.7759/cureus.103331.

7. Elethawi AM, Hamaamin SA, Mawlood TT, Qadir TO. Prevalence and associated risk factors of melasma among medical college students in Sulaymaniyah City: a cross-sectional study. J Adv Med Med Res. 2026;38(1):144-154. doi:10.9734/jammr/2026/v38i16048.

8. Aljinović-Vučić V. Self-medication as a global health concern: overview of practices and associated factors—a narrative review. Healthcare (Basel). 2025;13(15):1872. doi:10.3390/healthcare13151872.

9. González-Molina V, Martí-Pineda A, González N. Topical treatments for melasma and their mechanism of action. J Clin Aesthet Dermatol. 2022;15(5):19-28.

10. Al-Saleh I, Elkhatib R, Al-Rouqi R, Al-Enazi S, Shinwari N. The dangers of skin-lightening creams. Toxicol Environ Chem. 2012;94(1):195-219. doi:10.1080/02772248.2011.631925.

11. Polynice VM. Toxicity of mercury and hydroquinone in skin lightening products: popular practice in non-white communities [master's thesis]. Pittsburgh (PA): University of Pittsburgh; 2024.

12. Abbas E, Gul R, Hussain A. Prevalence of self-medication and assessment of its consequences on health among female university students in Islamabad, Pakistan. Proc Pak Acad Sci B Life Environ Sci. 2024;61(4):387-398. doi:10.53560/PPASB(61-4)942.

13. Ghasemiyeh P, Fazlinejad R, Kiafar MR, Rasekh S, Mokhtarzadegan M, Mohammadi-Samani S. Different therapeutic approaches in melasma: advances and limitations. Front Pharmacol. 2024;15:1337282. doi:10.3389/fphar.2024.1337282.

14. Passeron T, Liu W, Morita A, Goh CL, Alexis A, Dreno B, et al. Pigmentary disorders around the world: self-reported prevalence and impact on QOL and social stigmatization. J Invest Dermatol. 2026;146(6):1661-1668.e5. doi:10.1016/j.jid.2025.10.598.

15. Cassalia F, Ciolfi C, Scolaro F, Danese A, Lunardon A, Caroppo F, et al. Use of social media by the public regarding skin health: effects on dermatological awareness and preventive behaviours. Acta Derm Venereol. 2023;103:15341. doi:10.2340/actadv.v103.15341.

16. Algaadi SA, Almarshad SA, Abanmi HN, Alharfi RA, Almasoud SH. Public awareness of sun exposure risks and photoprotection for preventing pigmentary skin disorders in Saudi Arabia. J Pioneering Med Sci. 2026;15(S1):134-145. doi:10.47310/jpms202515S0126.

17. Alsatti H, Samarkandy SJ, Albogami DB, Alrajhi RK, Alahmadi RA, Alturkistani R, et al. The impact of social media on seeking dermatological care. Cureus. 2023;15(12). doi:10.7759/cureus.49941.

18. Alves Ferreira JM, Giannouli V, Tukaiev S. Disinformation, psychosocial vulnerability, and media trust in the digital era: implications for health behaviour and societal resilience. Healthcare (Basel). 2026;14(8):1089. doi:10.3390/healthcare14081089.

19. Salman M, Mallhi TH, Khan YH, Mustafa ZU, Khan MT, Rafaqat HH, et al. Non-prescription dispensing of controlled medicines at drug outlets in Pakistan: findings and implications to improve future health care. Adv Hum Biol. 2026;16(3):559-567. doi:10.4103/aihb.aihb_280_25.

20. Shakeel S, Iqbal Q, Riaz A, et al. Pharmacists' insights and behaviors in preventing the misuse of topical corticosteroids in Pakistan: a mixed-method study. Cosmetics. 2021;8(3):72. doi:10.3390/cosmetics8030072.

21. Corazza M, Borghi A, Lauriola MM, Virgili A. Use of topical herbal remedies and cosmetics: a questionnaire-based investigation in dermatology out-patients. J Eur Acad Dermatol Venereol. 2009;23(11):1298-1303. doi:10.1111/j.1468-3083.2009.03314.x.

22. Crous C, Pretorius J, Petzer A. Overview of popular cosmeceuticals in dermatology. Skin Health Dis. 2024;4(2). doi:10.1002/ski2.340.

23. AlRadini F, El-Sheikh A, Bin Jamaan N, Hushan H, Binhuwaimel W, Alhedaithy F, et al. Prevalence of over-the-counter cosmeceutical usage and the impact of a health education intervention in female Saudi university students. Clin Cosmet Investig Dermatol. 2021;14:1867-1877. doi:10.2147/CCID.S349440

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Published

2026-09-30

How to Cite

1.
Ijaz S, Yousaf S, Ahmad A, Zia F, Akram I, Arshad A, et al. Prevalence and Pattern of Self-Medication for Melasma among University Students: A Cross-Sectional Survey. Pak J Clin Res [Internet]. 2026 Sep. 30 [cited 2026 Oct. 23];3(9):19-24. Available from: https://pjcr.org/index.php/PJCR/article/view/317

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